The SGU podcast was first released in May 2005. The original lineup of the podcast consisted of the Novella brothers,
Steven Novella, Robert "Bob" Novella and Jay Novella, along with Evan Bernstein, and
Perry DeAngelis. DeAngelis contributed until his death in 2007, shortly before his 44th birthday.
Rebecca Watson joined in 2006 and later left the podcast in 2014.
Cara Santa Maria joined the cast in July 2015. The podcast is affiliated with the
New England Skeptical Society and with the SGU Productions LLC. Until late 2018 there were no full-time employees of the podcast. Co-host Jay Novella stated that this was partially a result of the financial drain from a protracted
defamation lawsuit, filed by
Edward Tobinick, which had "consumed financial resources that would have otherwise been available" for hiring staff. The transition to full-time status for Jay Novella was a result of three concurrent factors in 2018: the favorable resolution of the lawsuit, the end of Novella's existing career job, and the podcast successfully reaching its funding goal of over 3,000 patrons on
Patreon. As the podcast's first full-time employee, Novella's role expanded beyond co-host and website manager to focus on business operations, project management, and growing the podcast's audience, which included launching a new website and newsletter. == Production ==