The protein encoded by this gene is a member of the ISWI family of proteins. Members of this family have
helicase and
ATPase activities and are thought to regulate
transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the
chromatin remodeling and spacing factor
RSF, a facilitator of the transcription of class II genes by
RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. == Interactions ==