After playing one season in the second tier for
Östers IF, Jakobsson signed in 2007, at 17, for
national champion Umeå IK. In her five seasons in Umeå she won two championships and one
national cup, and she made her
UEFA Women's Cup debut. After Umeå lost its dominant position in the
Damallsvenskan since 2009, Jakobsson transferred to
Russian champion WFC Rossiyanka to again play the
UEFA Women's Champions League. Jakobsson signed for
Chelsea Ladies in January 2013. She scored on her debut in a 1–1 draw with
Birmingham, and then scored a brace in her next game against
Doncaster Rovers Belles. She scored in her third consecutive
Women's Super League game in a 2–1 win over the
Liverpool Ladies. She scored two more goals in the remaining eight games, ending as Chelsea's top scorer along with
Eniola Aluko. With three WSL games remaining until the end of the season she moved to the German
Bundesliga alongside teammate
Ester, signing for newly promoted team
BV Cloppenburg. In July 2014, Jakobsson signed for
Montpellier HSC of the French
Division 1 Féminine. In July 2019, Jakobsson joined
Real Madrid Feminino of the Spanish
Primera División, who at that time went under the name
CD Tacon, along with her national teammate,
Kosovare Asllani. During her first season in Spain, Jakobsson scored most goals and most assists in the capital club scoring eight goals and seven assists. In June 2021, Jakobsson announced that she was departing Real Madrid. On 2 July 2021, she signed with Bayern Munich in the top German league, the
Frauen-Bundesliga. Jakobsson made only five appearances with Bayern Munich, and in January 2022, was signed by the American team
San Diego Wave FC of the
National Women's Soccer League. On 11 September 2024, Jakobsson and the San Diego Wave agreed to a mutual contract termination. Jakobsson had played in 52 matches and made 30 starts in her tenure with the Californian club. Two days after the announcement of her departure from the Wave, Jakobsson signed with
Women's Championship club
London City Lionesses on a two-year contract. On 29 January 2026, Jakobsson and London City Lionesses agreed to mutually terminate her contract. The same day, she was announced at Toluca. ==International career==