Solasonine is one of the main components in the plant
Solanum nigrum Linn.. The plant has been used in traditional Chinese medicine due to its anti-inflammatory and anti-viral properties. Recent studies highlight the effects of solasonine and its anticancer potential by the suppression of tumor growth, inducing
apoptosis, and activating
ferroptosis. Solasonine enhances anticancer potential by inducing apoptosis, or programmed cell death, through the regulation of key pathways, such as the mitochondrial membrane permeability. Ferroptosis, a process that promotes cancer cell death, can be activated with solasonine by increasing and catalyzing
reactive oxygen species (ROS) production. == Side Effects ==