SC 357 begins at an
intersection with
SC 290 (East Poinsett Street) and
SC 101 (South Line Street) in Greer, and is named North Line Street until it intersects Arlington Avenue. At that point, road name changes to Arlington Road, and then intersects
U.S. Route 29 (US 29; East Wade Hampton Boulevard). From there, it goes down into unincorporated
Apalache, where it turns to the east, crosses the South
Tyger River, and then continues solely as SC 357. It intersects Gap Creek Road, and leaves Greer to enter
Lyman, South Carolina. Once SC 357 enters Lyman, it crosses the Middle Tyger River and goes on for a few miles until it crosses
SC 358, where SC 357 turns to the north and continues off of SC 358's terminus. SC 357 goes through some rural parts of Spartanburg County, which last until it reaches Campobello, South Carolina. Once the route enters Campobello, it intersects
US 176 (North Main Street), which is its northern terminus. ==History==