Spen may refer to:SPEN, human gene
Spen, West Yorkshire, a location in England
River Spen, river in West Yorkshire, England, the United Kingdom
SS Spen, British steamship built in 1908
SP Energy Networks, the energy networks arm of Scottish Power
People
• Spen King (1925–2010), British automobile designer • Spen Whittaker (1871–1910), English football manager ==See also==