A sperm donor is usually advised not to ejaculate for two to three days before providing the sample, to increase sperm count. A sperm donor produces and collects sperm at a sperm bank or clinic by
masturbation or during sexual intercourse with the use of a
collection condom.
Samples required per donor offspring The number of donor samples (ejaculates) that is required to help give rise to a child varies substantially from donor to donor, as well as from clinic to clinic. However, the following equations generalize the main factors involved: For
intracervical insemination: :N = \frac{V_s \times c \times r_s}{n_r} (
rs) varies with amount of sperm used in a cycle (
nr). Values are for intrauterine insemination, with sperm number in
total sperm count, which may be approximately twice the
total motile sperm count. (Old data, rates are likely higher today.) :
N is how many children a single sample can help give rise to. :
Vs is the volume of a sample (ejaculate), usually between 1.0
mL and 6.5 mL :
c is the concentration of motile sperm in a sample
after freezing and thawing, approximately 5-20 million per ml but varies substantially :
rs is the
pregnancy rate per cycle, between 10% and 35% :
nr is the
total motile sperm count recommended for vaginal insemination (VI) or intra-cervical insemination (
ICI), approximately 20 million pr. ml. The pregnancy rate increases with increasing number of motile sperm used, but only up to a certain degree, when other factors become limiting instead. With these numbers, one sample would on average help giving rise to 0.1–0.6 children, that is, it actually takes on average two to five samples to make a child. For
intrauterine insemination, a
centrifugation fraction (
fc) may be added to the equation: :
fc is the fraction of the volume that remains after centrifugation of the sample, which may be about half (0.5) to a third (0.33). :N = \frac{V_s \times f_c \times c \times r_s}{n_r} Only five million motile sperm may be needed per cycle with IUI (
nr=5 million) Thus, only one to three samples may be needed for a child, if used for IUI. Using
ART treatments such as
IVF can result in one donor sample (or ejaculate) producing on average considerably more than one birth. However, the actual number of births per sample will depend on the actual
ART method used, the age and medical condition of the female bearing the child, and the quality of the embryos produced by fertilization. Donor sperm is less commonly used for
IVF treatments than for
artificial insemination. This is because
IVF treatments are usually required only when there is a problem with the female conceiving, or where there is a 'male factor problem' involving the female's partner. Donor sperm is also used for
IVF in surrogacy arrangements where an embryo may be created in an
IVF procedure using donor sperm and this is then implanted in a surrogate. In a case where
IVF treatments are employed using donor sperm, surplus embryos may be donated to other women or couples and used in
embryo transfer procedures. When donor sperm is used for
IVF treatments, there is a risk that large numbers of children will be born from a single donor since a single ejaculate may produce up to 20 straws for IVF use. A single straw can fertilise a number of eggs and these can have a 40% to 50% pregnancy rate. 'Spare' embryos from donor treatments are frequently donated to other women or couples. Many sperm banks therefore limit the amount of semen from each donor which is prepared for
IVF use, or they may restrict the period of time for which such a donor donates his sperm to perhaps as little as three months (about nine or ten ejaculates).
Choosing donors Information about donor In the US, sperm banks maintain lists or catalogs of donors which provide basic information such as racial origin, skin color, height, weight, color of eyes, and
blood group. Some of these catalogs are available via the Internet, while others are only made available to patients when they apply for treatment. Some sperm banks make additional information about each donor available for an additional fee, and others make additional basic information known to children produced from donors when those children reach the age of eighteen. Some clinics offer "exclusive donors" whose sperm is only used to produce pregnancies for one recipient female. How accurate this is, or can be, is not known, and neither is it known whether the information produced by sperm banks, or by the donors themselves, is true. Many sperm banks will, however, carry out checks to verify the information requested, such as checking the identity of the donor and contacting his own doctor to verify medical details. In the UK, most donors are anonymous at the point of donation and recipients can only see non-identifying information about their donor (e.g., height, weight, ethnicity, etc.). Donors need to provide identifying information to the clinic and clinics will usually ask the donor's GP to confirm any medical details they have been given. Donors are asked to provide a pen portrait of themselves which is held by the
HFEA and can be obtained by the adult conceived from the donation at the age of 16, along with identifying information such as the donor's name and last known address at 18. Known donation is permitted and it is not uncommon for family or friends to donate to a recipient couple. Qualities that potential recipients typically prefer in donors include the donors being tall, college educated, and with a consistently high sperm count. A review came to the result that 68% of donors had given information to the clinical staff regarding physical characteristics and education but only 16% had provided additional information such as hereditary aptitudes and temperament or character. Sperm banks also screen out some potential donors based on height, baldness, and family medical history. The number of children permitted from a single donor varies by law and practice. These laws are designed to protect the children produced by sperm donation as well as the donor's natural children from
consanguinity in later life: they are not intended to protect the donor himself and those donating sperm will be aware that their donations may give rise to numerous pregnancies in different jurisdictions. Such laws, where they exist, vary from jurisdiction to jurisdiction, and a sperm bank may also impose its own limits. The latter will be based on the reports of pregnancies which the sperm bank receives, although this relies upon the accuracy of the returns and the actual number of pregnancies may therefore be somewhat higher. Nevertheless, sperm banks frequently impose a lower limit on geographical numbers than some jurisdictions and may also limit the overall number of pregnancies permitted from a single donor. The limitation on the number of children which a donor's sperm may give rise to is usually expressed in terms of 'families', on the expectation that children within the family are prohibited from sexual relations under incest laws. In effect, the term
family means a "woman" and usually includes the donor's partner or ex-partner, so that multiple donations to the same woman are not counted in the limit. The limits usually apply within one jurisdiction, so that donor sperm may be used in other jurisdictions. Where a woman has had a child by a particular donor, there is usually no limit on the number of subsequent pregnancies which that woman may have by that same donor. There is no limit to the number of offspring which may be produced from private donors. Despite laws limiting the number of offspring, some donors may produce substantial numbers of children, particularly where they donate through different clinics, where sperm is onsold or is exported to different jurisdictions, and where countries or jurisdictions do not have a central register of donors. Sperm agencies, in contrast to sperm banks, rarely impose or enforce limits on the number of children which may be produced by a single donor partly because they are not empowered to demand a report of a pregnancy from recipients and are rarely, if ever, able to guarantee that a female may have a subsequent sibling by the donor who was the biological father of her first or earlier children. In the media, there have been reports of some donors producing anywhere from over 40 offspring to several hundred or in one case, possibly over 1000.
Siblings Where a female wishes to conceive additional children by sperm donation, she will often wish to use the same donor. The advantage of having subsequent children by the same donor is that these will be full biological siblings, having the same biological father and mother. Many sperm banks offer a service of storing sperm for future pregnancies, but few will otherwise guarantee that sperm from the original donor will be available. Same sex couples looking to conceive with donor sperm also oftentimes use the same donor for multiple children in order to foster a greater biological connection between their children. In cases where both parents feel that pregnancy is appealing to them, they may decide to take turns getting pregnant in which case the siblings are only biologically related on the donor side. Sperm banks rarely impose limits on the numbers of second or subsequent siblings. Even where there are limits on the use of sperm by a particular donor to a defined number of families (as in the UK) the actual number of children produced from each donor will often be far greater. Since 2000, donor conceived people have been locating their biological siblings and even their donor through web services such as the
Donor Sibling Registry as well as DNA testing services such as
Ancestry.com and
23andMe. By using these services, donors can find offspring despite the fact that they may have donated anonymously.
Donor payment The majority of donors who donate through a sperm bank receive some form of payment, although this is rarely a significant amount. A review including 29 studies from nine countries found that the amount of money donors received varied from $10 to €70 per donation or sample. The payments vary from the situation in the United Kingdom where donors are only entitled to their expenses, to the situation with some US sperm banks where a donor receives a set fee for each donation plus an additional amount for each vial stored. At one prominent California sperm bank for example, TSBC, donors receive roughly $50 for each donation which has acceptable motility/survival rates both at donation and at a test-thaw a couple of days later. Because of the requirement for the two-day abstinence period before donation, and geographical factors which usually require the donor to travel, it is not a viable way to earn a significant income. Some private donors may seek remuneration although others donate for altruistic reasons. According to the
EU Tissue Directive donors in EU may only receive compensation, which is strictly limited to making good the expenses and inconveniences related to the donation. Equipment to collect, freeze and store sperm is available to the public notably through certain US outlets, and some donors process and store their own sperm which they then sell via the Internet. The selling price of processed and stored sperm is considerably more than the sums received by donors. Treatments with donor sperm are generally expensive and are seldom available free of charge through national health services. Sperm banks often package treatments into three cycles, and in cases of IVF or other ART treatments, they may reduce the charge if a patient donates any spare embryos which are produced through the treatment. There is often more demand for fertility treatment with donor sperm than there is donor sperm available, and this has the effect of keeping the cost of such treatments reasonably high.
Onselling There is a market for vials of processed sperm and for various reasons a sperm bank may sell-on stocks of vials which it holds (known as "onselling"). Onselling enables a sperm bank to maximize the sale and disposal of sperm samples which it has processed. The reasons for onselling may be where part of, or even the main business of, a particular sperm bank is to process and store sperm rather than to use it in fertility treatments, or where a sperm bank is able to collect and store more sperm than it can use within nationally set limits. In the latter case, a sperm bank may sell on sperm from a particular donor for use in another jurisdiction after the number of pregnancies achieved from that donor has reached its national maximum. ==Psychological issues==