This round was played from 28 to 30 October 2025 and featured the 16 winners from the previous round together with the 16 teams from the
Pro League, which were seeded and could not draw each other. The 6 non-professional teams left in the draw all received home advantage prior to the draw, with the exception of Eendracht Aalst Lede whose pitch was deemed unsuitable to host matches at this level, they were automatically assigned the away team role prior to the draw. As a result, due to these rules, Knokke and Tubize-Braine (both originally drawn away) were handed the home advantage after the draw. The draw was held on 8 September 2025. Three days after the draw, the mayor of Ninove prohibited the match against Anderlecht to take place in Ninove, citing the stadium was too small to safely host the match, after which the clubs agreed Ninove would give up home advantage and instead play the match in Anderlecht. ==Eighth round==