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St Mary's Hospital, London

St Mary's Hospital is a teaching hospital in Paddington, in the City of Westminster, London, founded in 1845. Since the UK's first academic health science centre was created in 2008, it has been operated by Imperial College Healthcare NHS Trust, which also operates Charing Cross Hospital, Hammersmith Hospital, Queen Charlotte's and Chelsea Hospital and the Western Eye Hospital.

History
Development of the hospital The original block of St Mary's Hospital in Norfolk Place was designed by Thomas Hopper in the classical style. It first opened its doors to patients in 1851, the last of the great voluntary hospitals to be founded. Among St Mary's founders was the surgeon Isaac Baker Brown, a controversial figure who performed numerous clitoridectomies at the London Surgical Home, his hospital for women, and who "immediately set to work to remove the clitoris whenever he had the opportunity of doing so." It was at St Mary's Hospital that C.R. Alder Wright first synthesized diamorphine in 1874. The Clarence Memorial Wing, designed by Sir William Emerson and built with its main frontage on Praed Street, opened in 1904. It was at the hospital that Alexander Fleming discovered penicillin in 1928. Fleming's laboratory has been restored and incorporated into a museum about the discovery and his life and work. it was financed by businessman and hospital board member Frank Charles Lindo, who made a large donation before his death in 1938. Also in 1937 the Lewis Carroll Ward for children was opened by the Queen. The ward was decorated with tile panels depicting scenes from Carroll's Alice in Wonderland. Following the 1944 publication of a report by Sir William Goodenough advocating a minimum size for teaching hospitals, and following the formation of the National Health Service in the 1948, several local hospitals became affiliated to St Mary's Hospital. These included Paddington General Hospital, the Samaritan Hospital for Women and the Western Eye Hospital. In the 1950s, Felix Eastcott, a consultant surgeon and deputy director of the surgical unit at St Mary's Hospital, carried out pioneering work on carotid endarterectomy designed to reduce the risk of stroke. Paddington General Hospital closed and relocated services to the Paddington basin site in November 1986 Notable births Royal familyAlexander Windsor, Earl of Ulster (born 1974) son of the Duke and Duchess of GloucesterLady Davina Windsor (born 1977) daughter of the Duke and Duchess of Gloucester • Peter Phillips (born 1977)son of the Princess Royal and Mark PhillipsLord Frederick Windsor (born 1979)son of Prince and Princess Michael of KentLady Rose Gilman (born 1980) daughter of Duke and Duchess of GloucesterZara Tindall (born 1981)daughter of the Princess Royal and Mark Phillips • Lady Gabriella Kingston (born 1981) daughter of Prince and Princess Michael of Kent • William, Prince of Wales (born 1982)first son of King Charles III and Diana, Princess of WalesPrincess Theodora of Greece and Denmark (born 1983)daughter of the King Constantine II of Greece and Queen Anne-Marie of GreecePrince Harry, Duke of Sussex (born 1984) second son of King Charles III and Diana, Princess of Wales • Prince Philippos of Greece and Denmark (born 1986) son of King Constantine II of Greece and Queen Anne-Marie of GreeceEdward Windsor, Lord Downpatrick (born 1988) son of George Windsor, Earl of St Andrews and Sylvana Windsor, Countess of St AndrewsPrince George of Wales (born 2013) first son of William, Prince of Wales, and Catherine, Princess of WalesPrincess Charlotte of Wales (born 2015) daughter of William, Prince of Wales, and Catherine, Princess of Wales • Prince Louis of Wales (born 2018) – second son of William, Prince of Wales, and Catherine, Princess of Wales Other notable birthsSeal (born 1963) British musician • Olivia Robertson (1917–2013) author, co-founder and High Priestess of the Fellowship of IsisElvis Costello (born 1954) British musician • Kiefer Sutherland (born 1966) Canadian actor • Lady Charlotte Wellesley (born 1990)daughter of the 9th Duke of Wellington • Michael Page (born 1987)British professional boxer and mixed martial artist • Louis Spencer, Viscount Althorp (born 1994) heir apparent to the Spencer earldom, nephew of Diana, Princess of Wales and first cousin of the Prince of Wales and the Duke of Sussex • Admiral Schofield (born 1997) American basketball player, currently with the Orlando Magic Notable staff and alumniArthur Cecil Alport physician who first identified Alport syndrome in 1927 • Roger Bannister first man to run a four-minute mile, professor of neurology • Dorothy Bannon – matron 1922–1928, subsequently first Chief Matron-in-Charge of the London County Council Hospital and School Nursing Service • Aleck Bournegynaecologist best known for his 1938 trial, a landmark case in abortion law • William Broadbent 19th-century neurologist and cardiologist • John Scott Burdon-Sanderson Regius Professor of Medicine at the University of Oxford and Royal Medal winner • J. Jackson Clarke pathologist, surgeon, and cancer researcher • Leonard Colebrook physician and bacteriologist, MBBS in 1906, who, in 1935, showed Prontosil was effective against haemolytic streptococcus of puerperal feverZachary Cope – surgeon and medical historian • Ara Darzi, Baron Darzi of Denham Health Minister • Alexander Fleming awarded the Nobel Prize for discovery of penicillinNim Hall England rugby captain • John Henry clinical toxicologist who did crucial work on poisoning and drug overdoseAmanda Herbert cytopathologist and histopathologist, editor of Cytopathology from 2008 to 2014 and co-editor of Eurocytology.euAlbert Neuberger professor of chemical pathologyTom Oppé professor of paediatrics • Tuppy Owen-Smith international rugby player and cricketer • William Stanley Peart professor of medicine, isolated and determined the structure of angiotensinRodney Robert Porter awarded the Nobel Prize for research on the chemical structure of antibodiesBernard Spilsbury pathologist and one of the pioneers of modern forensic medicineJoseph Toynbee otologistAugustus Waller whose research led to the invention of the electrocardiogram (ECG) • J. P. R. Williams international rugby player • Almroth Wright advanced vaccination through the use of autogenous vaccinesCharles Romley Alder Wright first person to synthesize heroin in 1874 • Wu Lien-tehlater to be the Plague fighter of China ==Associations==
Associations
St Mary's Hospital is located beside London Paddington railway station, the principal station of the Great Western Railway and its successors. In celebration of the association, a British Rail Class 43 (InterCity 125) locomotive, 43142, was named ''St Mary's Hospital, Paddington'' on 4 November 1986. The locomotive is still in service but, following changes of ownership, the name has now been removed. One of the large metal nameplates was acquired by the hospital, and is now displayed in the foyer of the Cambridge Wing. ==Major trauma centre==
Major trauma centre
St Mary's Hospital is one of four major trauma centres in London. The other three are King's College Hospital in Denmark Hill, The Royal London Hospital in Whitechapel, and St George's Hospital in Tooting. ==Cosmic charity==
Cosmic charity
The charity Cosmic is an independent charity, supporting the work of the neonatal and paediatric intensive care services at St Mary's Hospital, Paddington and Queen Charlotte's Hospital, Hammersmith, both part of Imperial College Healthcare NHS Trust, London. The charity funds a range of specialist equipment for the units, including ventilators and patient monitoring systems for those being treated on the wards, as well as providing practical and emotional support to families. == In popular culture ==
In popular culture
In the preschool animated television series Peppa Pig, Peppa's little sister Evie was born at the Lindo Wing on 20 May 2025. == See also ==
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