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Stanford V

Stanford V, is a chemotherapy regimen intended as a first-line treatment for Hodgkin lymphoma. The regimen was developed in 1988, with the objective of maintaining a high remission rate while reducing the incidence of acute and long term toxicity, pulmonary damage, and sterility observed in alternative treatment regimens such as ABVD. The chemical agents used are:A mustard derivative such as cyclophosphamide, chlormethine or ifosfamide Doxorubicin, an anti-tumor antibiotic Vinblastine, an alkaloid cell toxin Vincristine, another alkaloid cell toxin Bleomycin, another anti-tumor antibiotic Etoposide, a DNA toxin Prednisone, a corticosteroid

Drug Regimen
The chemotherapy part of Stanford V treatment can last anywhere from 8 to 12 weeks, depending on the staging of the disease. In many cases, this is followed by radiation therapy for anywhere from 2 to 6 weeks to the affected areas of the body. Stanford V is a more rigorously administered form of chemotherapy, with treatments roughly twice as fast as those of other Hodgkin lymphoma treatments. However, in a randomized controlled study, Stanford V was inferior to ABVD.{{cite journal |title=ABVD versus modified stanford V versus MOPPEBVCAD with optional and limited radiotherapy in intermediate- and advanced-stage Hodgkin's lymphoma: final results of a multicenter randomized trial by the Intergruppo Italiano Linfomi |journal=J. Clin. Oncol. |volume=23 |issue=36 |pages=9198–207 |year=2005 |pmid=16172458 |doi=10.1200/JCO.2005.02.907 ==References==
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