SR 185 begins at its intersection with
US 31 south of
Greenville. From this point, the route continues in a northerly track where it intersects
SR 10 just west of the Greenville
central business district. SR 185 continues north through the city and intersects both
SR 245 and
I-65 at Exit 130 prior to leaving the city limits. SR 185 then reorients in an easterly direction at
Fort Deposit and continues its course where it again intersects I-65 (Exit 142) prior to reaching its northern terminus at US 31. ==Major intersections==