Stavroupoli is a village and a former municipality in the Xanthi regional unit, East Macedonia and Thrace, Greece. Since the 2011 local government reform it is part of the municipality Xanthi, of which it is a municipal unit. The municipal unit has an area of 342.002 km2. Population 1,635 (2021). Stavroupoli and Nestos Valley including Nestos River Tempi is a popular tour region and vacation target in North Greece.