From 1984 to 1987, Manetti was a
parochial vicar at the . He was then an ecclesiastical assistant at the San Michele youth community until 1995. At the same time, he was ecclesiastical assistant for the youth section of
Azione Cattolica. In 1999, he became an ecclesiastical assistant for its adult section. In 1995, Manetti became the
pastor of the in
Certaldo. He was a religion teacher at the same time. In 2002, Manetti became the
spiritual director of the Archiepiscopal Major Seminary of Florence and was appointed a
canon of the
chapter of the
Basilica of San Lorenzo. In 2005, he was named the rector of the seminary and the head of vocations for the
Archdiocese of Florence. Manetti was then appointed a canon of the chapter of the
Cathedral of Santa Maria del Fiore and made an honorary canon of the chapter of the Basilica of San Lorenzo in 2009. He was also a member and coordinator of the archdiocese's
presbyteral council. In 2009, he was appointed to the archdiocese's
college of consultors. == Episcopal ministry ==