In June 2007, Lasme was selected in the second round, 46th overall, in the
2007 NBA draft by the
Golden State Warriors, using the pick they got from the
New Jersey Nets in exchange for
Clifford Robinson. He made his
NBA debut on November 8, playing only 3.8 seconds of game time in the Warriors 120–115 loss to the
Dallas Mavericks. On November 17, Lasme was waived by the Warriors. Later that month, he was signed by the
NBA Development League's
Los Angeles D-Fenders. On March 21, 2008, Lasme was signed to a ten-day contract with the
Miami Heat, whose roster had been depleted by injuries. He later signed for the rest of the season. In 15 games (four starts), he averaged 5.5 points, 3.5 rebounds, 1.5 blocks and 20.2 minutes. In September 2008, Lasme signed with the
Adriatic League champions
Partizan Belgrade, for the 2008–09 season. After the opening three games in
EuroLeague, he was ranked second in both blocks and rebounds per game. Lasme finished the season well, averaging 10.6 points, 6.6 rebounds, and 1.5 blocks per game, 25.5 minutes a contest, after Partizan's strong showing that ended in the quarterfinals with a loss to
CSKA Moscow. He was instrumental in helping the team to another
regional ABA championship, with 11.3 points per game. He also won
Serbian national championship and the Serbian
Radivoj Korać Cup titles with Partizan. In July 2009, Lasme signed with the
Israeli League club
Maccabi Tel Aviv, along with
Alan Anderson. On June 8, 2010, Maccabi announced that they had released Lasme, after a foot injury had limited his playing time towards the end of the season. In 20 games of EuroLeague play, he averaged 6.5 points, 4.4 rebounds, and 1.4 blocks per game in 18.5 minutes per game. Lasme then signed a two-year contract with the
Russian League club
Spartak Saint Petersburg in July 2010. However, he was released in September, due to some administrative problems that he had in the United States. Lasme was invited to join the
Boston Celtics for their 2010 training camp. However, he was waived on October 20. Subsequently, Lasme joined the
Maine Red Claws of the
NBA D-League, an affiliate of the Celtics. However, Lasme fractured his foot just 2 minutes into the team's preseason opener against the
Springfield Armor, and immediately underwent surgery. After recovering, he returned to action in March 2011. In August 2011, Lasme returned to Europe and signed with the
Spanish League newcomers
Obradoiro CAB. On July 5, 2012, the Boston Celtics announced that Lasme was added to their roster for the 2012
Orlando Pro Summer League and the
2012 NBA Summer League. On September 29, 2012, Lasme signed a one-year contract with the
Greek League club
Panathinaikos Athens. He was named the
EuroLeague Best Defender for the
2012–13 Euroleague season. He averaged 1.86 blocks and 6.14 rebounds per game, while his team allowed 69.8 points per game, thus displaying the second best team defense in the league. Also, Lasme earned the
Greek Basket League MVP award, as well as the
Greek League Best Defender award for the 2012–13 season. On July 1, 2013, Lasme renewed his contract with Panathinaikos for two more years. In May 2014, he was named to the
All-EuroLeague Second Team of the EuroLeague. He also earned the Greek League Best Defender award and was named to the
Greek League Best Five for the 2013–14 season. Panathinaikos decided to exercise an "opt out" clause in his contract for the upcoming 2014–15 season, on 12 June 2014. On June 22, 2014, he signed a two-year contract with
Anadolu Efes Istanbul. On July 29, 2015, he signed with
Galatasaray. Lasme was instrumental in winning the Eurocup title 2015–16, and earned the
Eurocup Finals MVP award. On August 29, 2016, Lasme was suspended for one year after failing a doping test. On February 10, 2017, Lasme was acquired by the
Texas Legends of the NBA Development League. On July 13, 2017, Lasme signed with Russian club
UNICS for the 2017–18 season. On June 27, 2018, Lasme officially returned to
Panathinaikos after four years, signing a one-year deal. In September 2022, Lasme returned from his retirement after four years when he joined the Gabonese club
Espoir to play for them in the
2023 BAL qualification tournament. Despite training with the team for a month, he did not join Espoir for their games in
Yaoundé,
Cameroon. ==National team career==