From 1983 to 1986, Amiel was a
research fellow at
Yale University. At Yale she undertook research in diabetes under professors William V. Tamborlane and Robert Stanley Sherwin. She then returned to England, and was a research fellow and honorary
senior registrar at
St Bartholomew's Hospital in the
City of London from 1986 to 1989. She is also a consultant physician to the diabetes services at
King's College Hospital NHS Foundation Trust. In 2018, she stepped down from the R. D. Lawrence Chair to become Professor of Diabetes Research. She then retired from full-time academia in 2021 and made
emeritus professor. Amiel's research continues to be focused on
type 1 diabetes. As a practising physician, she specialises in
intensive insulin therapy,
insulin pumps, and
diabetes in pregnancy. Her academic interests include
diabetic hypoglycaemia,
islet transplantation, and diabetes and
mental health. ==Personal life==