In September 2011, Coniglio confirmed he would nominate for the
2011 national draft, ending speculation about which sport he would choose to play professionally. Considered likely to be selected by with one of the first five picks in the draft, Coniglio was selected by Greater Western Sydney with pick two in the draft. He made his senior debut for the club in round one of the
2012 season, recording 17 disposals in a 63-point loss to . In round seven, after a 31-possession game in Greater Western Sydney's inaugural win over , Coniglio was nominated for the
2012 AFL Rising Star. Midway through the season, he injured his thumb, and missed four games after undergoing surgery. In total, he played 12 games for Greater Western Sydney in his debut season, spending parts of the latter half of the season with the club's
reserves team in the
North East Australian Football League (NEAFL). The end of the
2019 season saw Coniglio qualifying as a
free agent. Despite many rumours that he would leave and join a Victorian-based club, Coniglio had rejected massive offers from
Carlton and
Hawthorn and had re-signed with the Giants for a further seven years. At the end of 2019, Coniglio was awarded the
Jim Stynes Community Leadership Award for his part in the development of the Coniglio–Farrugia Community Program in partnership with the
New South Wales Government, as well as ambassador roles with the Fairfield Falcons Football Club, All Nations Cup, Diversity Talent and
Bachar Houli programs and the Lighthouse Community Support program. ==In the media==