Twitty is an
infantryman; his duty assignments include rifle platoon leader, scout platoon leader and battalion S-3 air officer from August 1985 to May 1989 with 1st Battalion, 327th Infantry Regiment, 101st Airborne (Air Assault) Division at Fort Campbell. From October 1989 to May 1993, he served as the S-3 air officer for 3rd Battalion, 7th Infantry Regiment during Operation Desert Storm; Aide-de-camp to the commanding general; and, commander of B Company, 3rd Battalion, 15th Infantry Regiment, 24th Infantry Division at
Fort Stewart, Georgia. From June 1999 to June 2001, Twitty served in Mons, Belgium at Supreme Headquarters Allied Powers Europe as the aide-de-camp to the Supreme Allied Commander Europe (SACEUR) and commander United States European Command, including during Operation Allied Response in Kosovo. From June 2003 to June 2004, he served as operations officer (G-3) for 3rd Infantry Division, Fort Stewart, Georgia. At Fort Bliss, he commanded 4th Brigade Combat Team,
1st Cavalry Division from August 2005 to March 2008, including during Operation Iraqi Freedom; later reflagged as 4th Brigade Combat Team, 1st Armored Division from March 2008 to July 2008. From July 2008 to July 2009, Twitty served as the executive officer to the deputy commanding general of U.S. Northern Command in Colorado Springs, Colorado. From July 2009 to September 2010, he served as the chief of staff, United States Army Central, Operation Iraqi Freedom. From September 2010 through March 2012, he served as the deputy commanding general (operations) for the 1st Armored Division at Ft. Bliss. From March 2012 to April 2013, Twitty served as the Deputy Chief of Staff for Strategic Communication, International Security Assistance Force (ISAF), Operation Enduring Freedom, Afghanistan. Twitty served as the Deputy Chief of Staff for Operations for
United States Army Forces Command at Fort Bragg, North Carolina. Twitty leaves First Army to serve as deputy commander of
EUCOM on 9 August 2018. ==Later career==