The
Monte Carlo method is a stochastic method popularized by physics researchers
Stanisław Ulam,
Enrico Fermi,
John von Neumann, and
Nicholas Metropolis. The use of
randomness and the repetitive nature of the process are analogous to the activities conducted at a casino. Methods of simulation and statistical sampling generally did the opposite: using simulation to test a previously understood deterministic problem. Though examples of an "inverted" approach do exist historically, they were not considered a general method until the popularity of the Monte Carlo method spread. Perhaps the most famous early use was by Enrico Fermi in 1930, when he used a random method to calculate the properties of the newly discovered
neutron. Monte Carlo methods were central to the
simulations required for the
Manhattan Project, though they were severely limited by the computational tools of the time. Therefore, it was only after electronic computers were first built (from 1945 on) that Monte Carlo methods began to be studied in depth. In the 1950s they were used at
Los Alamos for early work relating to the development of the
hydrogen bomb, and became popularized in the fields of
physics,
physical chemistry, and
operations research. The
RAND Corporation and the
U.S. Air Force were two of the major organizations responsible for funding and disseminating information on Monte Carlo methods during this time, and they began to find a wide application in many different fields. Uses of Monte Carlo methods require large amounts of random numbers, and it was their use that spurred the development of
pseudorandom number generators, which were far quicker to use than the tables of random numbers which had been previously used for statistical sampling. ==Biology==