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Strobilurin

Strobilurins are a group of natural products and their synthetic analogs. A number of strobilurins are used in agriculture as fungicides. They are part of the larger group of QoIs, which act to inhibit the respiratory chain at the level of Complex III.

Natural strobilurins
Strobilurin A : Strobilurin A (also known as mucidin) is produced by Oudemansiella mucida, Strobilurus tenacellus, Bolinea lutea, and others. When first isolated it was incorrectly assigned as the E E E geometric isomer but was later identified by total synthesis as being the E Z E isomer, as shown. 9-Methoxystrobilurin A 9-Methoxystrobilurin A is produced by Favolaschia spp. Later it was found in cultures of the basidiomycete fungi Mycena polygramma and Xerula melanotricha. The latter fungus also produces oudemansin B, with R1 = MeO and R2 = Cl. Oudemansin X, with R1 = H and R2 = MeO was isolated from Oudemansiella radicata. ==Synthetic strobilurins==
Synthetic strobilurins
The discovery of the strobilurin class of fungicides led to the development of a group of commercial fungicides used in agriculture. Examples are shown below. Image:Azoxystrobin.svg| Image:Trifloxystrobin.svg| Image:Kresoxim-methyl-2D-skeletal.png| Image:Pyraclostrobin.png| == See also ==
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