She was born in Meguro Village, Ebara County, Tokyo Prefecture (present day
Meguro-ku, Tokyo, Japan). Her sister Kiyoko Tagawa () was a dancer. Mizukubo attended the Senzoku High School for Girls |ja|洗足学園第一高等学校, before training at the revue and musical theatre company of
Shochiku alongside other future film actors such as
Yumeko Aizome and . Mizukubo acted at the Shochiku Kamata Studio and the Nikkatsu Tamagawa studios, She made her film debut in 1932 appeared in 39 movies as a young star, including films directed by
Naruse Mikio and
Ozu Yasujiro. She quit film-acting in 1935, but continued to dance and appear in stage roles with the
Yoshimoto Kogyo ==Filmography==