Before going pro in 2021, Ali Walsh spent a few months training alongside world-renowned boxing trainer,
Abel Sanchez, in Big Bear Lake, California. After having a "limited" amateur boxing career of approximately 30 bouts, Walsh decided to turn pro in early 2021. He began working with
Tyson Fury's current trainer,
SugarHill Steward, and is promoted by
Bob Arum's
Top Rank, who also promoted 27 of his grandfather's fights. Walsh made his professional debut against Jordan Weeks on the
Joshua Franco vs.
Andrew Moloney III undercard, on August 14, 2021. He won the fight by a first-round technical knockout. Walsh was booked to face James Westley II, in his second professional bout, on October 23, 2021, on the undercard of the WBO super featherweight championship between Shakur Stevenson and Jamel Herring. He won the fight by a third-round technical knockout. Walsh faced Reyes Sanchez on December 11, 2021, on the undercard of Vasyl Lomachenko vs Richard Commey. In his final fight of the year, He won the fight by a majority decision, with scores of 40–36, 38–38 and 39–37. Walsh faced Jeremiah Yeager on January 29, 2022, on the undercard of the WBC super featherweight title eliminator between
Robson Conceição and Xavier Martinez. He won the fight by a second-round technical knockout. Walsh faced Alejandro Ibarra on April 30, 2022, on the undercard of the WBC and WBO super featherweight unification between Shakur Stevenson and Óscar Valdez. He won the fight via 1st-round knockout. Walsh also said he hoped to stay active and fight again before he hit a year in professional boxing. Walsh fought again against Reyes Sanchez as Walsh did not like how he performed against him, as he thought the fight was close (one of the judges thought the fight was a draw, resulting in a majority decision). Walsh knocked out Reyes Sanchez in the second round at Pechanga Arena in San Diego, California.
Thrilla in Manila: The 50th Anniversary In August 2025, Walsh was announced to be participating in the commemorative event billed as "Thrilla in Manila: the 50th Anniversary" or "Thrilla in Manila II" that commemorates the historic
Thrilla in Manila clash between Walsh's grandfather
Muhammad Ali and
Joe Frazier. He boxed to a draw against Thai boxer Kittisak Klinson on October 29, 2025, at
Araneta Coliseum in
Quezon City, Philippines. ==Professional boxing record==