Main cast •
Kevin Heffernan as Fire Chief Terrance Leslie McConky. Lucy's father, married to Eddie's sister, Vicky. "Popped" a nut saving Eddie's life •
Steve Lemme as Captain Edward Caesar Penisi, Jr. Son of Fire Commissioner Edward "Eddie" Caesar Penisi, Sr. Lucy's uncle and Vicky's brother •
Marcus Henderson as Granfield "Granny" Smith. Paramedic of A-shift. •
Eugene Cordero as Kaponko "Andy" Myawani (seasons 1–3). Ike's best friend, also works at his uncle's carpet company, decides to take a permanent position there at the beginning of season 4. •
Gabriel Hogan as Ike Crystal. Andy's best friend a dim-witted rig engineer/driver, who is a stripper on the side, and has a twin brother named, Mike. •
Hassie Harrison as Lucy McConky. Daughter of Terry, formerly the rookie of A-shift until season 3, episode 2 (Hell Week). • Christopher Avila as Andres "Andy" Mickleberry (season 4). Newest rookie of A-shift.
Recurring cast •
Heather Mazur as Vicky Penisi–McConky, Terry's wife, Lucy's mother, Eddie Jr.'s sister and Eddie Sr.'s daughter • Kelsey Heffernan as Kelsey McConky, Terry and Vicky's daughter, Eddie Sr.'s granddaughter, Eddie Jr.'s niece and Lucy's sister • Quinn Heffernan as Quinn McConky, Terry and Vicky's daughter, Eddie Sr.'s granddaughter, Eddie Jr.'s niece and Lucy's sister •
Suzy Nakamura as Linda Price, a councilwomen of Tacoma's city council •
Paul Soter as Wolf Boykins, a firefighter and a Certification Trainer for the Tacoma Fire Department • Buck Heffernan as Hunter •
Alexie Gilmore as Hunter's mother •
Jamie Kaler as Captain Gerald "Jerry" Polonsky, Sr., captain of the Tacoma Police Department •
Jimmy Tatro as Sgt. Brad Shuck, Sergeant of the Tacoma Police Department • Maria Russell as Lt. Liz Salazar, Lieutenant of the Tacoma Police Department and Andy's ex-girlfriend •
Karen Maruyama as Mrs. Myawani, Andy's "mother," later revealed to be his grandmother • Anthea Neri Best as Kailani Myawani, Andy's "sister," later revealed to be his mother •
Nat Faxon as Frenchy, a member of the B-Shift on Station 24 •
Martin Starr as Toethar • Tina Arning as Lola Polonsky, Jerry's wife •
Jessica Lowe as Delilah •
Joe Pantoliano as Fire Commissioner Edward "Eddie" Caesar Penisi, Sr., Eddie and Vicky's father, Terry's father-in-law and Lucy's grandfather • Jeff Pierre as Captain Tad, captain of the C-Team on Station 24 •
Pierson Fode as Jan Damme, a member of the C-Team on Station 24 •
Brett Davis as Shorty, a member of the C-Team on Station 24 •
Jon Rudnitsky as Officer Gerald Polonsky, Jr., officer of the Tacoma Police Department •
Dexter Lumis as Dex •
David Arquette as Captain Teddy Dickosi ==Episodes==