Early life and start of his career Born in Nishiwasa city (now
Wakayama city), Saito's family moved to
Osaka soon after and opened a barbershop. He did not know he was born in Nishiwasa until he was 43 years old. After his father left the family to become a photographer, his mother raised Saito and his four siblings alone while working as a hairdresser.
Founding of Saitō Production and mainsteam breakthrough In April 1960, Saito left the Gekiga Kōbō and founded Saitō Production, a manga studio modeled on film production companies. This allowed for a hierarchical division of labor among staff, including scenario writers, pencillers, background artists, and tone applicators. By the late 1960s, Saitō Production had grown into a manga factory, standardizing output across multiple projects and genres while maintaining a distinctive “Saitō-Pro” style. The studio’s model emphasized efficiency over individual artistry, with Saito himself reportedly saying, "Even though I'm an artist, I'm not good at drawing pictures." Saito led the company until his death. Saito entered the mainstream manga industry in 1963 with
007, an adaptation of
Ian Fleming's
James Bond novels for
Shogakukan's ''
Boy's Life'' magazine. In 2013, Saito said "The manga has continued so long that it is no longer the property of the author; it belongs to the readers." It has been adapted into two live-action films, one animated film, an
OVA, an
anime TV series, and several video games. In 1971 Saito also started to give courses in drawing manga. Saito was a
director at , a publishing company spun-off from his Saito Production. It was founded in November 1974 and Saito's older brother was its president and CEO until his death in 2016. Following his brother's death, his brother's eldest son took over. In addition to many other products, Leed jointly publishes the
Golgo 13 tankōbon volumes with
Shogakukan. Saito illustrated an adaptation of
Shōtarō Ikenami's
Onihei Hankachō novel series that has been continuously serialized in Leed Publishing's
Comic Ran magazine since 1993, although a mistake by the editorial department resulted in the September 2019 issue becoming the first in 25 years to not include a chapter. He initially created it based on scripts by Sentarō Kubota (volumes 1–40), then on scripts by Kusumi Ohara from volume 40 until 53, when Ohara was joined by Kaori Moriyama.
Later life and death Saito said he suffered
retinal detachment at the age of 28 and was diagnosed as
diabetic at 48. He was a close friend of fellow manga artist
Shotaro Ishinomori. Saito died of
pancreatic cancer at 84 on September 24, 2021. His death was announced five days later by Shogakukan, along with his wish that
Golgo 13 continue on without him. The Saito Production group of manga creators continues its publication with the assistance of the
Big Comic editorial department. ==Reception and legacy==