Lysenko's first world record was a 77.06-metre throw, achieved on 15 July 2005 in
Moscow, beating the old record of
Mihaela Melinte by 0.99 metres. On 12 June 2006 she lost the record to her compatriot
Gulfiya Khanafeyeva, who threw 77.26 metres at the Russian athletics championships in
Tula. However, Lysenko threw 77.41 metres on June 24 in
Zhukovsky and 77.80 metres in Tallinn,
Estonia on August 15. On 21 July 2007 it was reported that she failed a
drug test, testing positive for a women's hormone blocker. In 2008, she was found guilty of using 6α-methylandrostendione and received a two-year ban (15.07.07 – 14.07.09) and disqualification of all results from 9 May 2007, including her world record of 78.61 m set on 26 May 2007. Lysenko returned to competition in July 2009, taking the Russian title with a 76.41 m throw. She won the gold at the
2010 IAAF Continental Cup and ranked third in the inaugural
IAAF Hammer Throw Challenge at the end of the year, with a combined score of 223.96 metres for her three best throws. In 2011, she won her first
world championship in the first world championships where the top three women all went over 75 m. She was awarded the
hammer throw gold medal at the
2012 London Olympics with a throw of 78.18 m. She won the
2013 World Championships with a world leading throw of 78.80 m. In May 2016
La Gazzetta dello Sport reported that a retest of Lysenko's samples from the 2012 Summer Olympics had tested positive for doping products, her third failure. If confirmed in the B sample, she stood to lose her Olympic and second World titles and faced a lifetime ban from the sport. In October, she was stripped of her Olympic gold medal. ==International competitions==