Sanford began his coaching career at Hargrave, coaching for thirteen years at the prep school. He became athletic director and coach of the baseball and basketball teams at
Randolph–Macon. His teams won a total of five conference championships over his seven years in
Ashland, Virginia, before moving to
Wake Forest as freshman football coach. In his second year at Wake Forest, he added baseball to his coaching duties while continuing in various assistant coaching roles with the football team. Most notably, the Deacs won the
Atlantic Coast Conference and College World Series in 1955. Sanford also headed the Wake Forest team when it was selected as the representative
United States national team at the
1951 Pan American Games in Buenos Aires, Argentina. The Wake Forest team, which was the first U.S. national team to participate in international competition since the
1942 Amateur World Series, took the silver medal. During the College World Series, a rainout forced a game on Sunday, sparking a small controversy at the Baptist school when word reached Wake Forest. This followed word that Sanford would not be kept full-time after the 1956 season and little recognition from the school of his achievement in Omaha. Sanford therefore resigned from Wake Forest on January 31, 1956, citing his "feeling of insecurity" and that he had "no assurance that I will have a job after the current season is over." ==Later life and death==