After completing his doctorate, Wang joined the
California Institute of Technology's
Jet Propulsion Laboratory (JPL) in 1972, as a senior scientist. At JPL he was responsible for the inception and development of containerless processing science and technology research. He was the Principal Investigator (PI) on the Spacelab 3 mission NASA Drop Dynamics (DDM) experiments, PI on the NASA SPAR Flight Experiment #77-18 "Dynamics of Liquid Bubble," PI on the NASA SPAR Flight Experiment #76-20 "Containerless Processing Technology," and PI on the Department of Energy Experiment "Spherical Shell Technology." He gained US
citizenship in 1975, and published a paper on the dynamic behavior of rotating spheroids in
zero gravity the next year. The paper received attention in
NASA, and Wang was selected as a payload specialist on June 1, 1983, for the
Spacelab-3 mission. Wang conducted precursor drop dynamics experiments for the DDM in ground-based laboratories employing
acoustic levitation systems, neutral buoyancy systems and drop towers, and in the near-weightless environment provided by JSC's KC-135 airplane flights and SPAR rockets. These flights have helped to define the experimental parameters and procedures in the DDM experiments performed on Spacelab 3. He is the inventor of the acoustic levitation and manipulation chamber for the DDM. (Wang, T.G., M. Saffren, D. Elleman and J.C. Fletcher (1975) Material Suspension Within an Acoustically Excited Resonant Chamber. U.S. Patent No. 3,882,732)
Spaceflight Wang flew on
STS-51-B Challenger (April 29 – May 6, 1985). STS-51B/Spacelab-3 was launched from Kennedy Space Center, Florida, and returned to land at Edwards Air Force Base, California. It was the first operational Spacelab mission. The seven-man crew aboard
Challenger conducted investigations in crystal growth, drop dynamics leading to containerless material processing, atmospheric trace gas spectroscopy, solar and planetary atmospheric simulation, cosmic rays, laboratory animals and human medical monitoring. Wang was the principal designer of an experiment called the Drop Dynamics Module, which aimed to uncover the fundamental physical behavior of liquid drops in microgravity. Despite his extensive preparation, the experiment malfunctioned upon activation. Wang, feeling immense pressure and aware of the high expectations from the Chinese community, became deeply despondent. When Wang's experiment failed, he desperately negotiated with NASA flight controllers for a chance to repair it, even threatening not to return if not allowed to fix the instrument, telling NASA flight controllers "Hey, if you guys don't give me a chance to repair my instrument, I'm not going back." Wang received permission to attempt a fix and was successful in repairing the experiment, though his remark caused concern for the safety of the crew and the mission. The incident was covered in an
Ars Technica article on 22 January 2024. There,
John Fabian, mission specialist on
STS-51-G, the very next shuttle flight after 51-B, was cited to explain why a lock was recently installed on the door of the side hatch: "It was installed when we got into orbit so that the door could not be opened from the inside and commit
hara-kiri, kill the whole crew. That was not because of anybody we had on our flight but because of a concern about someone who had flown before 51-G."
Post-spaceflight research Using insights from compound droplet experiments performed in the microgravity of NASA Shuttle Mission STS-51-B, Dr. Taylor Wang, has developed an
immunoisolation encapsulation system that protects cellular transplants, and sustains cell function — without immunosuppression drugs and their resulting negative side effects. This novel immunoisolation system is a multi-component, multi-membrane capsule that allows independent optimization of all capsule design parameters ensuring reproducible functions in large animals and humans. Results of Encapsulife's successful large animal trials, have recently been published in peer-reviewed research in Transplantation Journal. In this landmark research, encapsulated canine pancreatic islets were transplanted into dogs rendered diabetic by total pancreatectomy. No immunosuppression or anti-inflammatory therapy was used. The allotransplantations of encapsulated islets were well tolerated and biocompatible, and normalized fasting blood glucose levels in all of 9 dogs, were achieved for over two hundred days, with a single transplantation. Re-transplantation of encapsulated islets — a "booster" — was effective in providing glycemic control beyond the initial 200 days.
Professorship Wang later became a Centennial Professor at
Vanderbilt University in
Nashville,
Tennessee. He has written about 200 journal articles and holds 28 U.S. patents on acoustics, drops and bubble dynamics, collision and
coalescence of drops, charged drop dynamics, containerless science, and encapsulation of living cells. His experiments were carried out in 1985 aboard United States Spacelab 3, and in 1992 aboard United States Microgravity Laboratory 1 (USML-1), and in 1995 aboard USML-2. ==Recognition==