Although Watkins Street begins at Union Avenue in Memphis and passes through
North Memphis and the Frayser neighborhood, the state route designation begins at the intersection of Watkins Street and Thomas Street (
US 51/
SR 3). Continuing north, SR 388 crosses over the
Loosahatchie River; this is the last crossing before the river empties into the
Mississippi River. After this crossing, SR 388 passes to the east of the Northaven community. Continuing northward, SR 388 abruptly ends at the two-lane Locke–Cuba Road. By turning onto this road, one can get to the Shelby Forest community and
Meeman-Shelby Forest State Park. ==History==