The Mobile–Tensaw River Delta and the adjacent Mobile estuary make up one of the largest wetland ecosystems in the United States, which is why protecting its wide range of biodiversity is a top priority for conservators. According to the Forever Wild ranking system, the Mobile-Tensaw Delta is one of its top priorities for protection. The Alabama Department of Conservation and Natural Resources (ADCNR) Game and Fish Division has also listed the Mobile-Tensaw Delta as one of their highest priorities for inclusion into the state wildlife management area system. The delta is one of 327 watersheds (of the 2,100 in the United States) to be deemed as being of irreplaceable value to conserving populations of all freshwater fish and mussel species at risk. Conservators' wide range of obstacles include hydrological alterations from man-made developments, stream pollution, the effects of upstream dams on stream flow, and effects of exotic invasive plant and animal species. The construction of the causeway in the 1920s is considered one of the most significant man-made obstructions to the delta. The causeway restricts sediment and water exchange with Mobile Bay resulting in an immensely higher sedimentation rate. The loss of hydrological connectivity between the delta and Mobile Bay reduced the salinity of the surrounding rivers and bay. Several species of fish, crustaceans, shellfish, and plant communities have been altered as a result of reduced salinity. Human activities resulting in upstream pollution within the Mobile River Basin have profound impacts on the Mobile-Tensaw Delta. Such pollution can include sediments, trace elements, metals, and pesticides draining from the basin upstream. Trace elements detected in fish tissue collected from sites throughout the Mobile River Basin suggest that aluminum, boron, copper, iron, manganese, selenium, strontium, and zinc are the most prevalent trace elements in the water. Upstream dams are put into place most commonly for the purposes of power generation, navigation, and flood control. Dams distort the natural hydrological flow by either physically restricting movement of wildlife or by creating large areas of inhospitable habitat. In both cases, populations are isolated, which can have detrimental effects on reproduction and natural migration. The Claiborne Lock and Dam, the largest dam upstream of the Mobile water basin, is located in Monroe County, Alabama. Exotic invasive plant and animal species have permanently altered the Mobile–Tensaw River Delta's ecology. Both types pose a threat to the native populations of wildlife that call the Mobile Delta home. Some of the most common non-native invasive plant species to conquer the delta include Eurasian watermilfoil, hydrilla, water hyacinth, and common salvinia. The most common invasive invertebrates include the Amazonian
apple snails,
Asiatic clams, and subtropical water fleas. Invasive fishes include common carp and grass carp. The invasive species that poses the largest threat to the entire ecosystem is wild swine. They are detrimental to the entire Alabama ecosystem because they eat almost any type of plant or animal materials, including agricultural crops, food discarded by humans, carrion, small mammals, birds, turtles, snakes, and amphibians. Humans are considered the only significant threat to this invasive hog population, which is why they are one of the only hunted animals in the state that are not monitored by a season for hunting. ==Recreation==