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TFMFly

TFMFly, or TFM-FLY, also known as DOTFM-FLY, is a serotonin receptor modulator of the phenethylamine, amphetamine and DOx, and FLY families related to psychedelics like DOTFM and DOB-FLY.

Pharmacology
Pharmacodynamics It acts as a potent agonist at the 5HT2A serotonin receptor subtype, and is a chiral compound with the more active (R) enantiomer having a Ki of 0.12 nM at the human 5-HT2A receptor. While the fully aromatic benzodifurans such as Bromo-DragonFLY generally have higher binding affinity than saturated compounds like 2C-B-FLY, ==Chemistry==
Chemistry
Synthesis The chemical synthesis of TFMFly has been described. Analogues Analogues of TFMFly include DOTFM, DOB-FLY, and 25TFM-NBOMe, among others. ==History==
History
TFMFly was first reported by a team at Purdue University led by David E. Nichols in 2001. ==Society and culture==
Society and culture
Legal status Latvia TFMFly is illegal in Latvia. ==See also==
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