The previous film, ''
The Castaways on Gilligan's Island, had been produced as a pilot for a potential series set at The Castaways resort in a similar fashion to The Love Boat'', but
NBC had decided not to proceed. Nonetheless, a sequel to the film was commissioned, following the newly established format. NBC executives brought the idea to have the
Dallas Cowboys Cheerleaders appear in a ''
Gilligan's Island'' special to original series creator
Sherwood Schwartz. Schwartz liked the idea and agreed to produce a two-hour TV-movie based on this premise. Before the script was completed,
NBC informed Schwartz the cheerleaders would not be available and asked him to rewrite the script with the
Harlem Globetrotters instead, which Schwartz agreed to do. At the time of filming
Jim Backus was unable to reprise his role due to ill health from
Parkinson's disease. Sherwood Schwartz refused to recast Thurston Howell III with another actor, feeling it would hurt Backus too much. So instead, he rewrote the script, writing out Thurston Howell III by having him tend to business in the mainland United States, and adding a new character, Thurston Howell IV, the son of the Howells (played by
David Ruprecht) to manage the island resort (although this contradicted the original series, where the Howells were childless). Schwartz was impressed with Ruprecht's performance in maintaining a Howell-like persona without being an imitation of Backus. Toward the end of filming, Backus insisted that he felt well enough to make a cameo appearance and was written in as having returned from his business trip, at the end of the movie. Sherwood Schwartz and
Dawn Wells both recalled how emotional it was on set that day as Backus filmed his short scene. He was weakened and very shaky as he said his few lines, but he still dominated his character as before; after he finished his scene, he asked Wells, "Was I funny?" Wells assured him that he was, although she broke into tears afterwards. As Backus left the set with his longtime wife
Henny and his caretaker, there was an emotional round of applause for him, from the cast and crew, many of whom were in tears. Backus, who was also in tears, stopped, and responded to the applause by blowing kisses to everybody before he left. He was credited alongside the main cast in the opening scene as "Thurston Howell III", and Ruprecht was credited at the end of the opening with "and introducing David Ruprecht as Thurston Howell IV". Neither of the previous actresses who played Ginger agreed to reprise their role in this film.
Bob Denver's wife, Dreama, having previously appeared in an episode as a cavewoman, appeared as Lucinda, Mrs. Howell's overly punctual secretary. This was the final performance together of
Martin Landau and
Barbara Bain, the husband-and-wife team best known for their starring roles in
Mission: Impossible and
Space: 1999. They divorced in 1993. Like the original sitcom, ''The Harlem Globetrotters on Gilligan's Island'' featured a
laugh track. ==Release==