Development On April 18, 2018, it was announced that
National Geographic had given a series order to the production. Executive producers were set to include Lynda Obst, Kelly Souders, Brian Peterson, Jeff Vintar, and Ridley Scott. Production companies involved with the series were slated to consist of
Fox 21 Television Studios,
Scott Free Productions, and Lynda Obst Productions. On August 9, 2018, it was announced that Kelly Souders and
Brian Wayne Peterson were joining the series as showrunners, executive producers, and writers. On February 8, 2019, it was announced that the series would premiere on May 27, 2019. In November 2020, National Geographic renewed the series for a second season.
Casting On July 25, 2018, it was announced during the
Television Critics Association's annual summer press tour that
Julianna Margulies had been cast in the first season's lead role. On September 13, 2018, it was reported that
Noah Emmerich,
Liam Cunningham,
Topher Grace,
Paul James,
Nick Searcy,
Robert Wisdom, and
Robert Sean Leonard had joined the cast in starring roles and that
James D'Arcy would make a guest starring appearance. On December 6, 2018, it was announced that
Grace Gummer would appear in a recurring capacity. In early 2021, following the announcement of a second season with a different story,
Tony Goldwyn, Exterior photography of the rear loading docks of the "monkey lab" took place at the now-closed Life Savers Factory located at 100 Cumberland Ave,
Hamilton, Ontario. Loading docks can be viewed from Burris Street as well as homes in reverse shots. Exterior and interior shots of "Commuter Station" took place at the historic Hamilton Canadian National Railway Station, located at 360 James St N, in Hamilton, Ontario. == Release ==