The episode's plot contains a theme of equality and civil rights. "The Mutants Are Revolting" has been interpreted as a political warning against societies with a "disposable
class" of people. It has also been interpreted as a statement about the plight of
undocumented immigrants, due in part to Leela's secret status as an "illegal alien" in the series (as mutants are not allowed to live on the surface). Mr. Astor giving up his seat on the "lifeboat" for Leela's grandmother and great-grandmother may be a reference to Alfred Vanderbilt, a wealthy passenger on the
Lusitania, who gave his life belt to a young woman and her child, though he himself could not swim. Ms. Astor, who invites the crew to the party, has a meal delivered that contains Nitroglycerin. This chemical is very explosive and is produced by nitrating glycerol with white fuming nitric acid under conditions appropriate to the formation of the nitric acid ester. The episode also contains several cultural references, including references to
P. L. Travers' character
Mary Poppins, and the 1997 film
Titanic. The song "
Bend It" by the British 1960s pop group
Dave Dee, Dozy, Beaky, Mick & Tich is used in this episode. The "Westside Pipeway" scene is reminiscent of a scene in the 1927 silent film
Metropolis. Leela also refers to the uprising of the mutants as the 'Million Mutant March' which references the '
Million Man March'. The episode also contains self-references, such as the inclusion of many one-time and recurring characters in the background of Bender's party scene. When Devo appear, they are asked to play "
Whip It", their most successful single. Refusing, they decide to play "the other one" and perform "
Beautiful World", one of only a few singles of theirs to find mainstream success. Near the end of the episode, Fry divides the wave of waste in two, preventing it from hitting the mutants and saying "let my people stay", which is a reference to the
Crossing of the Red Sea and the "
Go Down Moses" song. After this happens, one mutant says "Are we not men!", a reference to Devo's song "
Jocko Homo", which includes the lyric "Are we not men? We are Devo", and also to their first album,
Q. Are We Not Men? A. We Are Devo!. ==Broadcast and reception==