Main •
Robbie Amell as Stephen Jameson,
(voice only), the Tomorrow People's artificial intelligence, originally stolen from Ultra by John and now currently resident in the Tomorrow People's lair, actively assisting in coordinating their retrieval and recovery of other Tomorrow People from apprehension and murder by Ultra and its henchmen. •
Madeleine Arthur as Charlotte Taylor (A child telepath. Charlotte was experimented on at "The Citadel", an anti-telepath prison, but is later rescued by the Tomorrow People.) She appears to be closest to John. •
Ben Hollingsworth as Agent Troy •
Carly Pope as Morgan Burke, Jedikiah's girlfriend who is a Tomorrow Person and in the sixteenth episode, it is revealed that she is pregnant with his child. •
Nicholas Young as Aldus Crick, a scientist who worked with Roger Price on researching the abilities of
Homo superior. He was killed by Ultra. Nicholas Young played John in the original 1973–1979 series. •
Serinda Swan as Cassandra Smythe, the Founder's daughter and a powerful synergist. Her father used her as a guinea pig for unknown experiments. She was accidentally killed by the Founder when he used his telekinesis to deflect a bullet that was meant for him. •
Simon Merrells as Hugh Bathory, better known as "the Founder". An extremely powerful and experienced Tomorrow Person, mysterious head of Ultra, father of Cassandra Smythe and considered a monster. At the end of the series, he disappears into a vortex caused by the malfunction of a time stasis apparatus. •
Leven Rambin as Natalie, a troublemaking telepath with no love for "Saps". Later, she becomes a coldblooded Ultra operative and tries to murder Cara, but is prevented by Stephen's newly disclosed time reversal abilities, which stop the event from ever happening. •
Laura Slade Wiggins as Irene Quinn, a 17-year-old Tomorrow Person and geneticist. ==Episodes==