Detry turned professional in June 2016 and started competing on the
Challenge Tour. He made the cut in his first 10 professional events, culminating in his win at the 2016
Bridgestone Challenge. With this win, he equaled the record for lowest under-par finish ever on the Challenge Tour (29 under par, set in 2003 by
Ivó Giner), and set a new record for the win by the widest margin ever on the Challenge Tour – 12 strokes ahead of the second-place finisher. He also broke the course record at
Heythrop Park Resort with his first round of 60 (12 under par). In August
2020, Detry twice finished solo runner-up at tournaments on the European Tour, at the
Hero Open in
Birmingham, England and at the
Celtic Classic at the
Celtic Manor Resort in Wales, both times beaten by
Sam Horsfield, and advanced to 75th on the
Official World Golf Ranking. In February 2025, Detry became the first Belgian to win on the
PGA Tour when he won the
WM Phoenix Open. He won by seven shots ahead of
Daniel Berger and
Michael Kim. ==Amateur wins==