Thomas Drake was born on 14 January 1749 the second but oldest surviving son of
William Drake, MP for Amersham from 1746 to 1796, and his wife Elizabeth, daughter of John Raworth of
London. He was educated at
Westminster School and
Brasenose College, Oxford. His elder brother was
William Drake, who predeceased their father. Thomas adopted the surname Tyrwhitt in 1776 in order to inherit the estates of his cousin Sir John de la Fountain Tyrwhitt, 6th Baronet, and then the additional surname of Drake in 1796 when his father died. Together, they had five sons and three daughters: •
William Tyrwhitt-Drake (1785 - 1848) was a Member of Parliament for Amersham from 1810 to 1832. •
Reverend John Tyrwhitt-Drake, Rector of Amersham, married Mary Annesley, third daughter of Arthur Annesley of Bletchingdon, Oxfordshire. He married secondly Emily Drake-Garrard, fifth daughter of
Charles Drake Garrard. •
Reverend George Tyrwhitt-Drake, Rector of Malpas, Cheshire. He married Jane Halsey, second daughter of Joseph Halsey of Gaddesden. • Frederick William Tyrwhitt-Drake. • Mary Frances Tyrwhitt-Drake. • Anne Tyrwhitt-Drake. She married
Hugh Richard Hoare, of Lillingstone, Buckinghamshire. • Louisa Isabella Tyrwhitt-Drake. She married
the Rev. John Anthony Partridge, rector of Cranwich, Norfolk. He held the post of
Sheriff of Glamorganshire for the year 1786-7 and was commissioned into the Amersham Volunteer Infantry as a Captain in 1798. ==Member of Parliament==