From 1832 to 1846 Stone and his family resided in East Machias, Maine, where he was pastor of the Union Church. As seen by his writing and lectures during this time, Stone became an early convert to abolitionism. As early as the 1830s Thomas Stone was exhorting his congregation that slavery was a national problem. "It was the duty of all Christians", according to Stone, "to do our utmost in resisting [slavery], through the Spirit of Christ." East Machias was home to many intellectuals at that time, and his church members included many who later took on theological leadership positions in New England educational institutions. Among them were
Samuel Harris (President of Bowdoin College and Professor of Theology at
Yale Divinity School),
Roswell Dwight Hitchcock (President, Union Theological Seminary), Ezra Abbott (
Harvard Divinity School), George Harris (Andover Theological School), and
Arlo Bates (professor at MIT). Stone lectured for the Massachusetts England Anti-slavery Society, and was a delegate to the 1839 annual meeting of that group. His sermon
The Martyr of Freedom, a discourse delivered at East Machias, in 1837, condemned the killing of
Elijah Lovejoy, Stone's friend and an anti-slavery publisher in Illinois. Lovejoy was a Presbyterian minister editing anti-slavery newspapers in Missouri until his presses were destroyed by mobs. Lovejoy was killed during an attempt to burn his office in Alton, Illinois. In his sermon Stone urged his listeners to "proclaim the truth of slavery, not only to peers, but to the slaveholder." Slavery, he stated, not only destroys those who witness truth but the nation and slaveholder as well. These strong abolitionist viewpoints led to Stone's ousting as a Congregationalist minister in 1844. In 1846 he moved his family from Maine to Massachusetts to become pastor of the First Church of Salem (Massachusetts, Unitarian), where he served until 1852. During this time he was able to build his anti-slavery fervor, as evidenced by frequent visits by the elite of the movement, including
Amos Bronson Alcott,
Ralph Waldo Emerson,
John Greenleaf Whittier,
William Lloyd Garrison, and
Wendell Phillips. Reactions among many New Englanders to the passage of the
Fugitive Slave Act of 1850 was mixed, but to those who opposed slavery it was fierce. Discontent among Stone's parishioners at First Church in Salem rose as he became more involved with the fugitive slave issue. In August 1851, Stone was formally terminated. His fate was similar to other New England theologians, many who resigned or were dismissed for supporting the anti-slavery cause. In December 1851 Stone addressed the Salem Female Anti-Slavery Society in Salem, of which his wife, Laura Poor Stone, was a member. An abolition quilt she created there is owned by the Peabody Essex Museum.{{ cite web | archive-url= https://web.archive.org/web/20120422142851/http://www.salemwomenshistory.com/First_Church_in_Salem.html | archive-date= 22 April 2012| url-status= usurped ==Transcendentalism==