In 1998, Penicheiro joined the Sacramento Monarchs as a rookie, finishing third in the
WNBA Rookie of the Year award voting. As a four-time
WNBA All-Star player, she has twice tied the WNBA's record with 16 assists in a single game. In 1999, she was selected as a WNBA first-team player. This was also the year she set her WNBA high in points, with 27 against the
Minnesota Lynx. In 2001, she was selected as a member of the WNBA's second team. She had, as of June 19, 2003, 1,027 career points in the WNBA; for an average of 6.8 per game, 1,121 assists; for a total of 7.5 per game, 615 rebounds; for a total of 4.1 per game, and 322 steals, for a total of 2.15 per game. Penicheiro retired as the all-time WNBA leader in total assists and assists per game, although both records have since been surpassed, respectively by
Sue Bird and
Courtney Vandersloot. Penicheiro also holds the WNBA single-game record for most steals with 10. After the Monarchs franchise became defunct, Penicheiro signed with the
Los Angeles Sparks. In 2011, her second year with the team, she was voted in by fans as one of the Top 15 players in the fifteen-year history of the WNBA. In February 2012, Penicheiro signed with the
Chicago Sky, but her season statistics were significantly diminished due to injuries, and on September 18, she announced that she would retire from the WNBA at the end of the 2012 season. Penicheiro was inducted into the
Virginia Sports Hall of Fame in 2014. In 2016, Penicheiro was named in the
WNBA Top 20@20, a list of the WNBA's top 20 players of all time in celebration of the league's twentieth anniversary. She was also named to the WNBA's 25th anniversary team,
The W25, in 2021. ==WNBA career statistics==