Main characters • Tigtone (voiced by
Nils Frykdahl as an adult,
Cree Summer as a child) – The primary protagonist, a wandering adventurer with an obsession for quests. • Helpy (voiced by
Debi Derryberry) – An unspecified creature and Tigtone's companion whose regenerative powers make them regularly exploited and abused, even after becoming friends with Tigtone. In the finale of the first season, Helpy was revealed to have used Tigtone's quests to gather items needed for their master The Greater Good, only to subsequently be betrayed by The Greater Good and make amends with Tigtone. • King-Queen (King voiced by
Bill Corbett and Queen voiced by
Lucy Davis) – The two-headed ruler of Propecia. One head is a male who is a king and the other head is a female who is a queen. In season two, it was revealed that the queen half of King-Queen had an affair with the late court wizard Amothedeus which led to Lavender killing the king half and send the queen half into exile. The queen half starts to hallucinate seeing her husband's ghost, as she plans to reclaim her kingdom. In "Tigtone and the Stakes", upon Helpy getting the queen half to Propecia, the king half is revived by Lavender as the king half apologizes to Lavender for not being his real dad. • Lore Mastra (voiced by
Cree Summer) – The intense keeper of the royal library who often acts as a dispatcher for Tigtone's quests. She is prone to unpredictable fits of rage. • Prince Lavender (voiced by
Jeffrey Combs) – The man-child son of King-Queen. In the second season, Lavender finds out that his true father is the late Amothedeus, making him a half-wizard leading to him killing the king half of King-Queen and driving the queen half into exile. He then collaborates with Spaceress in plots to take down Tigtone. By the end of the second season, Prince Lavender revives the king half of King-Queen while reconciling with his parents and maintaining his love for Spaceress. • Command-Or Mathis (voiced by
Trace Beaulieu) – The put-upon attendant of King-Queen, who frequently attempts to impress the monarch, but is constantly overshadowed by Tigtone's accomplishments. In "Tigtone and the Stakes," Mathis is turned to stone during the fight against Lavendar and Spaceress.
Recurring characters • Memory Gnome (voiced by
John DiMaggio in the pilot,
Gary Anthony Williams in later episodes) – A gnome who dispenses advice to Tigtone through memories. • Lord Festus (voiced by
Sid Haig in the pilot,
John DiMaggio in later episodes) – A recurring villain with a fetish for torturing people. • Beconka (voiced by
Cree Summer) – A wandering adventurer who becomes Tigtone's competitive rival. • Spaceress (voiced by
Maria Bamford) – An evil space villain who ends up on Tigtone's world at the start of the second season. She allies with Prince Lavender and he falls in love with her. The episode "Tigtone and the Seven-Headed Serpent of Kloom" reveals that she is just an alien worm in a robotic armor. ==Episodes==