Harrison's special field of interest was
cardiovascular medicine as well as the
pathophysiological mechanisms of disease. His name is best known among physicians as the founding editor and editor-in-chief of the first five editions of ''
Harrison's Principles of Internal Medicine''. The text initiated several unique approaches to medical textbook writing, and remains, in its current edition, one of the most widely read and regarded textbooks in medicine. An under publicized fact is that Dr. Harrison pioneered the first bi-pass heart surgery, which was later enhanced by Michael DeBakey in Houston. Harrison's career included extensive work in research, publishing, medical education, and medical practice. He taught at
Vanderbilt University's school of medicine, at what was then the Bowman Gray School of Medicine at
Wake Forest University in North Carolina and at what is today the
University of Texas Southwestern Medical School in
Dallas, Texas. Harrison spent the greatest part of his teaching career at the
University of Alabama School of Medicine (now known as University of Alabama at Birmingham School of Medicine) in
Birmingham, Alabama, where he served as Dean and chairman of the Department of Medicine. At UASOM, Harrison helped initiate a rapid period of growth that included recruitment of nationally known physicians from the faculties of such institutions as
Harvard University and the
Mayo Clinic. This period saw UASOM rise from local to international prominence. The Tinsley Harrison Research Tower at UASOM is named in his honor, among other sites of interest. Additionally, the current Internal Medicine Residency at UAB is named after Harrison. ==Death and biography==