After leaving the University of Manchester, he worked for the former Chief Rabbi, the late
Lord Sacks, from 1994 to 1996. From 1998 to 2008, he was a consultant at
McKinsey. From 2017 to 2020, he was chief executive of Be the Business, a government and industry-funded body launched by
George Osborne aiming to make British companies more productive. In June 2020, it was announced that he would be the next director general of the Confederation of British Industry (CBI): he succeeded
Carolyn Fairbairn in November 2020. On 11 April 2023, the CBI announced that Danker had been dismissed with immediate effect as his conduct had "fallen short of that expected of the director general". Danker said that had been made "the fall guy" for a wider crisis at the organisation. In January 2024 it was announced that the CBI had settled on undisclosed terms an action for wrongful dismissal brought against it by Danker. ==Views==