Topchikhinsky District is an administrative and municipal district (raion), one of the fifty-nine in Altai Krai, Russia. It is located in the center of the krai. The area of the district is 3,300 square kilometers (1,300 sq mi). Its administrative center is the rural locality of Topchikha. Population: 23,350 (2010 census); 27,305 (2002 census); 27,528 (1989 Soviet census). The population of Topchikha accounts for 37.8% of the district's total population.