At 7 a.m.
CST (13:00
UTC), a
low-pressure area of about was over eastern Oklahoma and western Arkansas, with warm air moving north from the
Gulf of Mexico to the
Mississippi Valley. Conditions in Alabama and Mississippi were mostly cloudy with early thunderstorm activity, yet temperatures were already in the low 70s and upper 60s
°F in Mississippi and western Tennessee. By afternoon, temperatures rose to the middle to upper 70s °F across most of the area. As a
cold front approached Alabama, forecasters predicted afternoon thunderstorms and an end to the warm temperatures but did not anticipate the magnitude of the severe weather that later hit most of the state from north of
Montgomery to the Tennessee and Georgia borders. As the outbreak progressed, ten F4 tornadoes struck Alabama,
Tennessee, and
Georgia. In Alabama, within four hours of the first F4 tornado, 18 people were killed near the
Cullman area in
Cullman County; 14 in the
Columbiana area in Shelby County; 41 in Coosa and
Talladega counties near
Sylacauga; and 38 people in other small communities in Northeastern Alabama, mostly in
Jackson County. One of the tornadoes followed the deadly Jemison event by one hour and passed just to the southeast, killing 31 people in and around the
Clanton area in Chilton County. Outside Alabama, six people were killed near
Pulaski, Tennessee, in
Giles County. 13 people in the state died from this and six other strong tornadoes. In Georgia and Tennessee, a large tornado near the state line left a mile-wide damage path, and killed 15 people from
Beaverdale, Georgia, to
Conasauga, Tennessee. Two other tornadoes in Georgia killed a combined 16 people and were on the ground almost simultaneously. On March 22, tornadoes continued after midnight CST (06:00 UTC) as four more strong tornadoes struck Georgia and South Carolina until 2:00 a.m. CST (08:00 UTC). One of them passed near the
University of Georgia in
Athens and killed 12 people. ==Confirmed tornadoes==