Predecessor institutions Toronto Rehabilitation Institute (TRI or Toronto Rehab) was formed through a series of
rehabilitation hospital mergers, with a direct lineage of care dating to the 19th century. The Toronto Home for Incurables opened in 1874 at Bathurst and King Streets, to receive long-term care patients from
Toronto General Hospital, primarily those with untreatable forms of tuberculosis, heart disease and paralysis. In 1880, the home was moved into larger premises on Dunn Avenue in suburban
Parkdale and was expanded several times in the following years. In the mid-century, the home was renamed the Queen Elizabeth Hospital for the Incurables then the Queen Elizabeth Hospital. In 1975, it became the first chronic care teaching hospital in Canada, affiliated with the
University of Toronto. The hospital then expanded, constructing an additional facility at Dunn Ave. and purchasing a former building of
Mount Sinai Hospital on University Ave. In 2019, UHN consolidated the programs of the TRI Research Institute as KITE (knowledge, innovation, talent, everywhere) at UHN, led by research director Dr.
Milos R. Popovic. == Programs ==