He returned to the United States in 1892 to continue boxing. On 6 February 1892, he was knocked out by Johnny Griffith in a 122 pound Featherweight Title match in Brooklyn, New York. Both boxers complained of injuries to their hands, not uncommon considering the thin gloves used in most bouts. In an unusual match on 16 December 1893, in Paterson, New Jersey, with
George Dixon, Murphy was disqualified in the third round for a blow to the referee. Dixon had the best of the first round. Trying to break the fighters from clinching in the third round, Murphy hit Referee James Stoddard with a right in the face either accidentally or distracted by the heat of the moment, and infuriated, Stoddard retaliated with two quick blows that landed Murphy under the ropes. The house became wild, but the police managed to keep order. Some papers described the fight as a knockout, though the referee, not Dixon put Murphy on the mat.
Losses to champions Dixon, Santry, Forbes, and Harris He fought
George Dixon on 22 January 1897 at the Broadway Athletic Club in Brooklyn, losing in a six round knockout. The fight was billed as a 120 pound World Featherweight Title match. Manager Sam Fitzpatrick had predicted that Dixon would have the edge in the bout. As the bout was with a former World Champion, it attracted considerable interest, and Dixon led the betting by odds of 2 to 1. Murphy held his own for the first three rounds, but looked fatigued by the last three, while Dixon remained fresh and unfazed by the blows of Murphy. Murphy was knocked down and out in the sixth by a strong left to the stomach. On 26 November 1898, he was knocked out by a rising Chicago star,
Eddie Santry, who would take the World Featherweight Championship, according to most sources, the following year against English boxer Ben Jordan. Murphy's knockout loss to Santry took place in the fourth round at the Commercial Athletic Club in St. Louis, Missouri. On 29 April 1899, he lost in a four round knockout to future World Bantamweight Champion
Harry Forbes at the Chicago Athletic Association in Chicago, Illinois. On 19 May 1899, he lost to 1901 World Bantamweight Champion
Harry Harris in a fourth round knockout at the Star Theatre in Chicago. ==Return to Australia in 1904==