US 69 begins at its southern terminus with
SH 87 in Port Arthur. This intersection is also the southern terminus for
US 96 and
US 287, which are concurrent with US 69. US 69, US 96, and US 287 continue in a northwest, then west, route until its intersection with
Interstate 10 in southern
Beaumont. At this intersection, US 69, US 96, and US 287 merge with I-10. I-10/US 69/US 96/US 287 continue in a northerly direction through Beaumont for several miles. Just after the intersection with
US 90, I-10 splits from the multiplex and resumes its easterly course, leaving US 69, US 96, and US 287 heading northwest through Beaumont. US 69 north of I-10 is also known officially known as
Eastex Freeway, and is an official evacuation route, just as
Interstate 69/
US 59 heading north from Houston is known as Eastex Freeway as well. In Lumberton,
US 96 splits from US 69 and
US 287 and heads northeast towards
Jasper, while US 69 and US 287 continue on a northwest path towards
Woodville. In Woodville, US 69 splits from
US 287 a few blocks north of
US 190. US 287 continues northwest towards
Corrigan while US 69 proceed north towards
Lufkin. In this area, between US 190 in Woodville and FM 256 in
Colmesneil, US 69 is a part of the
Texas Forest Trail. Before reaching Lufkin, US 69 forms another segment of the Texas Forest Trail between
SH 63 in
Zavalla and
FM 1818 northwest of Zavalla. In Lufkin, US 69 is concurrent with
US 59 and
State Loop 287 while the route through the city is named Business US 69. US 69, State Loop 287, and US 59 continue around the east side of Lufkin until US 59 separates at the intersection with
US 59 Business northeast of Lufkin. US 69 and State Loop 287 continue until the intersection of
SH 103 and Business US 69 on the northwest section of Lufkin. At that point, US 69 is concurrent for a short distance with SH 103 and State Loop 287. At the intersection of US 69, State Loop 287 and SH 103, US 69 departs Lufkin and heads northwest while SH 103 and State Loop 287 head south. US 69 continues on a north to northwest path through the towns of
Alto,
Rusk,
Jacksonville and
Bullard. Just south of Bullard, US 69 has a short concurrency with
FM 2493. US 69 continues northward into
Tyler. In Tyler, US 69 continues northward through the city until the intersection of
SH 110 and
SH 155, where US 69 heads west and merges with SH 110 and SH 155 through Tyler. Around seven blocks from the intersection of US 69, SH 110, and SH 155, SH 155 separates from the concurrency and travels in a southwesterly direction, leaving US 69 and SH 110 traveling in a northwesterly direction. This continues until SH 110 separates from US 69 on the northwest side of Tyler. At this intersection, SH 110 heads west while US 69 continues north. US 69 crosses
Interstate 20 at
Lindale where it is signed as "Main Street". At
FM 16 in Lindale, US 69 begins its third and last segment as part of the Texas Forest Trail. US 69 continues north to northwest to
Mineola, crossing
US 80 there. Before leaving town, at its intersection with
SH 37, the Texas Forest Trail turns off of US 69 to share a segment with SH 37. US 69 takes a more northwest turn on its way through several small towns, including
Emory, on its way to
Greenville. There, as it begins to enter the city, a Business route of US 69 turns off to the right to serve the downtown Greenville area, and then on to a junction with
Interstate 30. At the intersection with I-30, US 69 becomes concurrent with
US 380 at its terminus. The concurrency continues around the southern and western sides of Greenville until an intersection with
Spur 302. At that intersection, US 380 heads west while US 69 continues north, until it reaches the northern end of its Business route, which has passed through the downtown Greenville area, then US 69 turns northwest, from Greenville to
Leonard, where it encounters a brief concurrency with
SH 78. In
Whitewright,
SH 11 intersects and becomes concurrent with US 69 southeast of town. This continues until the intersection with
SH 160, at which time SH 11 continues on a northwestward route and US 69 continues north through Whitewright. US 69 continues north, then northwest until
Denison, where it turns right to go north, at an intersection with
Spur 503. US 69 goes north through downtown Denison, then at the north side of town, US 69 intersects and merges with
US 75, at which time US 69 becomes concurrent with US 75. Both head northeast across the Oklahoma/Texas border at the
Red River. ==Future==