The NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) supports the development and evaluation of new, revised, and alternative methods for chemical safety testing.
Alternative methods are methods for safety testing of chemicals and chemical products that use fewer or no animals or that minimize or prevent animal pain and distress. NICEATM is directed by Dr. Warren Casey, PhD,
DABT. The NIH Revitalization Act of 1993 directed NIEHS to establish criteria for the validation and regulatory acceptance of alternative test methods and a process for their subsequent implementation. This led to the establishment of the
Interagency Coordinating Committee on the Validation of Alternative Methods via the ICCVAM Authorization Act of 2000, which stated that ICCVAM would exist as a permanent interagency committee of NIEHS under NICEATM. In addition to supporting ICCVAM, NICEATM activities include: • Conducting and publishing analyses and evaluations of data from new, revised, and alternative testing approaches • Providing information to test method developers, regulators, and regulated industry through its website and other communications and by organizing workshops and symposia on topics of interest • Providing bioinformatics and computational toxicology support to National Toxicology Program and NIEHS projects, especially those related to
Tox21 NICEATM publishes results of its analyses of alternative test methods and approaches in the peer-reviewed literature and presents at meetings of the
Society of Toxicology and the
World Congress on Alternatives and Animal Use in the Life Sciences. ==Office of the Report on Carcinogens==