The Club was founded as "Club Deportivo, Social y Cultural Ferrocarril Urquiza" by Carmelo Santoro on May 21, 1950. The first players and fans of the team were employees of the
General Urquiza Railway who needed a ground to play football on Saturday afternoons. The club affiliated to the
Argentine Football Association in 1970 and played its first season in the "Aficionados" division (the fourth level of
Argentine football league system, later renamed "
Primera D"). At the beginning of the
2009–2010 season the club merged with Universidad Abierta Interamericana (UAI) to form "Club Deportivo UAI-Urquiza". Having won no titles under its old name, UAI Urquiza obtained the first season disputed by the team, the 2009–10 Primera D championship, promoting to
Primera C. In May, 2013, UAI Urquiza won the Primera C champions, therefore promoting to the upper division,
Primera B Metropolitana. The squad beat
Deportivo Español by 3–1, when there still had 4 fixtures to play. At the moment of the championship, UAI Urquiza had taken an advantage of 13 points over
Deportivo Laferrere, the team placed 2nd. ==Stadium==