The event marked the promotion's return to Brazil for the first time since
UFC Fight Night: Lee vs. Oliveira, which took place in
Brasília in March 2020. That event took place
behind closed doors (for the first time in the promotion's history) after
Ibaneis Rocha, the
governor of the
Federal District (where Brasília is located), announced that large gatherings had been suspended due to the
COVID-19 pandemic. A
UFC Light Heavyweight Championship bout for the vacant title between former champion
Glover Teixeira and
Jamahal Hill headlined the event. Teixeira was originally expected to compete at
UFC 282 as a challenger in a rematch against then-champion
Jiří Procházka, but Procházka pulled out and vacated the title after a serious shoulder injury. Teixeira subsequently refused a replacement fight against
Magomed Ankalaev, which prompted the UFC to change the original co-main event between former champion
Jan Błachowicz and Ankalaev into the new title fight for the vacant belt. After that contest ended in a split draw, the organization decided to book Teixeira and Hill, who was scheduled to headline
an event against former title challenger
Anthony Smith in early March. Smith was expected to serve as an alternate for the title bout. However, he weighed in at 206.5 pounds on his second attempt and was unable to compete if necessary. A
UFC Flyweight Championship unification tetralogy bout between current two-time champion
Deiveson Figueiredo and former champion/current interim title holder
Brandon Moreno took place at the event. The pairing first met at
UFC 256 on December 12, 2020, which ended in a majority draw (Figueiredo retained the title). Their second meeting took place at
UFC 263 on June 12, 2021, where Moreno captured the title by submission in the third round. Their third meeting took place at
UFC 270 on January 22, 2022, where Figueiredo regained the title by unanimous decision.
Alexandre Pantoja served as backup and potential replacement for this fight. A women's featherweight bout between
Josiane Nunes and
Zarah Fairn took place at the event. They were originally scheduled to meet at
UFC on ESPN: Whittaker vs. Gastelum in April 2021, but on the day of the weigh-ins Fairn weighed in at 147 pounds, eight pounds over the pre-established limit of 139 pounds (the bout was originally set for the women's bantamweight division, but was shifted to a catchweight prior to the start of the weigh-ins). The bout was cancelled due to the weight discrepancy, as Nunes weighed in at 136 pounds. A heavyweight bout between
Shamil Abdurakhimov and
Jailton Almeida took place at the event. They were previously scheduled to meet at
UFC 279 and
UFC 280 but Abdurakhimov withdrew both times due to visa issues and for undisclosed reasons respectively. Guram Kutateladze was expected to face
Thiago Moisés in a lightweight bout at this event. However, Kutateladze pulled out in early January for undisclosed reasons. He was replaced by promotional newcomer Melquizael Costa. A middleweight bout between
Brad Tavares and former
LFA Middleweight Champion Gregory Rodrigues was expected to take place at the event. However, Tavares withdrew from the bout due to an injury. He was replaced by promotional newcomer Brunno Ferreira. During the event's broadcast, the inaugural and former two-time
UFC Featherweight Champion José Aldo (also former
WEC Featherweight Champion) was announced as the next "modern wing"
UFC Hall of Fame inductee. ==Results==