A heavyweight bout between former
UFC Heavyweight Championship challenger
Derrick Lewis and
Chris Daukaus headlined the event. A women's strawweight bout between
Amanda Lemos and
Nina Nunes was scheduled for the event. However, Nunes was removed from the bout due to undisclosed reasons and was replaced by former
Invicta FC Strawweight Champion Angela Hill. A middleweight bout between
Anthony Hernandez and
Dustin Stoltzfus was scheduled for the event. However, Hernandez withdrew from the event due to undisclosed reasons and was replaced by newcomer
Caio Borralho. In turn, Borralho and
Gerald Meerschaert's opponent,
Abusupiyan Magomedov, were forced to withdraw from the fight due to visa issues, thus the UFC matched Meerschaert and Stoltzfus against each other for the event. A women's bantamweight bout between former
UFC Women's Bantamweight Championship challenger
Raquel Pennington and
Julia Avila was scheduled for the event. However, Avila was forced to pull out of the event due to injury. She was replaced by
The Ultimate Fighter: Heavy Hitters featherweight winner
Macy Chiasson, thus changing the contest to the weight class above. A bantamweight bout between
Raoni Barcelos and
Trevin Jones was scheduled for the event. However, Jones withdrew from the fight due to undisclosed reasons and was replaced by Victor Henry. The pairing was then cancelled just hours before taking place due to
COVID-19 protocols. At the weigh-ins, three fighters missed weight for their respective bouts.
Justin Tafa weighed in at 267 pounds, one pound over the heavyweight non-title fight limit (marking the first time in UFC history that a fighter missed weight in that division);
Sijara Eubanks weighed in at 127.5 pounds, 1.5 pounds over the women's flyweight non-title fight limit; and Macy Chiasson weighed in at 148.5 pounds, 2.5 pounds over the women's featherweight non-title fight limit. All three bouts proceeded at a catchweight with Tafa, Eubanks and Chiasson each fined a percentage of their purses, which went to their opponents Harry Hunsucker,
Melissa Gatto and
Raquel Pennington respectively. ==Results==