A featherweight bout between
Bryce Mitchell and
Movsar Evloev was expected to headline the event. However, Evloev withdrew in mid October due to injury and the bout was scrapped. A women's strawweight bout between
Marina Rodriguez and
Amanda Lemos was originally expected to take place at
UFC 280, but was postponed to this event for unknown reasons. After the original main event was cancelled, they were promoted to the headliner spot. A women's flyweight bout between
Miranda Maverick and
Shanna Young took place at this event. The pair was previously scheduled for
UFC 278, but the bout was cancelled on the day of the weigh-ins as Young was hospitalized due to weight cut issues.
Neil Magny and
Daniel Rodriguez were scheduled to meet in a welterweight bout at
UFC Fight Night: Grasso vs. Araújo in October 15, but Rodriguez withdrew due to an elbow infection. They were then rescheduled for this event. Jailton Almeida and
Maxim Grishin were previously scheduled to meet in a light heavyweight bout at
UFC Fight Night: Holm vs. Vieira, but the latter pulled out due to undisclosed reasons back then. They were rebooked for this event in a catchweight of 220 pounds, after Almeida was in need of a new opponent as
Shamil Abdurakhimov pulled out due to undisclosed reasons of their heavyweight bout at
UFC 280. The bout was reportedly scrapped from this card on fight week due to undisclosed reasons. At the weigh-ins, a record-tying four fighters missed weight: •
Grant Dawson weighed in at 157.5 pounds, one and a half pounds over the lightweight non-title fight limit. •
Benito Lopez weighed in at 138.5 pounds, two and a half pounds over the bantamweight non-title fight limit. • Carlos Candelario weighed in at 127.5 pounds, one and a half pounds over the flyweight non-title fight limit. • Ramona Pascual weighed in at 137 pounds, one pound over the bantamweight non-title limit. All four bouts proceeded at catchweight. Dawson was fined 30% of his purse while Lopez, Candelario, and Pascual were fined 20% of their individual purses which went to their opponents
Mark Madsen,
Mario Bautista, Jake Hadley, and Tamires Vidal, respectively.
Josh Parisian was expected to face
Chase Sherman in a heavyweight bout. However, he pulled out of the fight hours before it was scheduled to take place due to medical issues. ==Results==